Publications

CircumVent Project is backed by peer-reviewed research validating its implementation, and a protocol for effective use of the technology in low-cost, low resource settings. Papers published through the project are listed below:

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The CircumVent Project: a CPAP/O2 helmet solution for non- invasive ventilation using an implementation research framework.

Ahonkhai AA, Musa AZ, Fenton AA, Aliyu MH, Ofotokun I, Hornstein A, Musa BM, Nwosu N, Ulasi I, Ajayi S, Falade C, Dada A, Abdu A, Sunday M, Odewabi A, Rotimi MK, Ogueh O, Steinbach A, Ogedegbe G, Salako BL, Ezechi OC. The CircumVent Project: a CPAP/O2 helmet solution for non- invasive ventilation using an implementation research framework. Implement Sci Commun. 2021 Aug 26;2(1):93. doi: 10.1186/s43058-021-00193-y. PMID: 34446110; PMCID: PMC8390034.

The CircumVent Project: A CPAP/O2 Helmet Solution for Non-Invasive Ventilation Among Patients With COVID-19 (CircumVent)

Ahonkhai AA, Musa AZ, Fenton AA, Aliyu MH, Ofotokun I, Hornstein A, Musa BM, Nwosu N, Ulasi I, Ajayi S, Falade C, Dada A, Abdu A, Sunday M, Odewabi A, Rotimi MK, Ogueh O, Steinbach A, Ogedegbe G, Salako BL, Ezechi OC. The CircumVent Project: a CPAP/O2 helmet solution for non-invasive ventilation using an implementation research framework. Implement Sci Commun. 2021 Aug 26;2(1):93. doi: 10.1186/s43058-021-00193-y. PMID: 34446110; PMCID: PMC8390034.

Related
Publications

Related research in helmet ventilation and ventilation in low-resource settings was critical to the development and implementation of CircumVent.  External work that influenced the CircumVent Project are listed in the bibliography below:

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Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections.

Simonds, A. K., Hanak, A., Chatwin, M., Morrell, M. J., Hall, A., Parker, K. H., ... & Dickinson, R. J. (2010). Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections. Health technology assessment, 14(46 Article 2), 131-172.

One year outcomes in patients with acute respiratory distress Syndrome enrolled in a randomized clinical trial of helmet versus facemask noninvasive ventilation.

Patel, B. K., Wolfe, K. S., MacKenzie, E., Salem, D., Esbrook, C. L., Pawlik, A. S., ... & Kress, J. P. (2018). One year outcomes in patients with acute respiratory distress Syndrome enrolled in a randomized clinical trial of helmet versus facemask noninvasive ventilation. Critical care medicine, 46(7), 1078.

Effect of noninvasive ventilation delivered by helmet vs face mask on the rate of endotracheal intubation in patients with acute respiratory distress syndrome: a randomized clinical trial.

Patel, B. K., Wolfe, K. S., Pohlman, A. S., Hall, J. B., & Kress, J. P. (2016). Effect of noninvasive ventilation delivered by helmet vs face mask on the rate of endotracheal intubation in patients with acute respiratory distress syndrome: a randomized clinical trial. Jama, 315(22), 2435-2441.

Noninvasive ventilation with helmet versus control strategy in patients with acute respiratory failure: a systematic review and meta-analysis of controlled studies.

Liu, Q., Gao, Y., Chen, R., & Cheng, Z. (2016). Noninvasive ventilation with helmet versus control strategy in patients with acute respiratory failure: a systematic review and meta-analysis of controlled studies. Critical Care, 20(1), 1-14.

Cost analysis of noninvasive helmet ventilation compared with use of noninvasive face mask in ARDS.

Kyeremanteng, K., Gagnon, L. P., Robidoux, R., Thavorn, K., Chaudhuri, D., Kobewka, D., & Kress, J. P. (2018). Cost analysis of noninvasive helmet ventilation compared with use of noninvasive face mask in ARDS. Canadian respiratory journal, 2018.

Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask.

Hui, D. S., Chow, B. K., Lo, T., Ng, S. S., Ko, F. W., Gin, T., & Chan, M. T. (2015). Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask. Chest, 147(5), 1336-1343.

Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks.

Hui, D. S., Chow, B. K., Lo, T., Tsang, O. T., Ko, F. W., Ng, S. S., ... & Chan, M. T. (2019). Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks. European Respiratory Journal, 53(4).

Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.

Delivered by Helmet vs Face Mask on the Rate of Endotracheal Intubation in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial. JAMA. 2016;315(22):2435–2441.

Covid-19 research guidance for MSHS. Research Roadmap.

Covid-19 research guidance for MSHS. Research Roadmap. (n.d.). Retrieved March 29, 2022, from http://researchroadmap.mssm.edu/reference/covid-19-guidance/#ventilator-repurpose

Covid-19 - trying not to intubate early & why ardsnet may be the wrong ventilator paradigm: AAEM - American Academy of Emergency Medicine.

Covid-19 - trying not to intubate early & why ardsnet may be the wrong ventilator paradigm: AAEM - American Academy of Emergency Medicine. AAEM. (n.d.). Retrieved March 29, 2022, from https://www.aaem.org/resources/publications/podcasts/critical-care-in-emergency-medicine/episode-19

Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and metaanalysis of randomized controlled trials.

Cabrini, L., Landoni, G., Oriani, A., Plumari, V. P., Nobile, L., Greco, M., ... & Zangrillo, A. (2015). Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and metaanalysis of randomized controlled trials. Critical care medicine, 43(4), 880-888.